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024 7 _a10.1007/978-3-031-25588-5
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072 7 _aMED106000
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072 7 _aMBGR
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082 0 4 _a610.72
_223
245 1 0 _aElectromechanobiology of Cartilage and Osteoarthritis
_h[electronic resource] :
_bA Tribute to Alan Grodzinsky on his 75th Birthday /
_cedited by Brianne K. Connizzo, Lin Han, Robert L. Sah.
250 _a1st ed. 2023.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2023.
300 _aXIV, 173 p. 1 illus.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
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347 _atext file
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490 1 _aAdvances in Experimental Medicine and Biology,
_x2214-8019 ;
_v1402
505 0 _aPreface (Brianne K. Connizzo, Lin Han, Robert L. Sah) -- Scientific Impact -- Chapter 1. Aggrecan and Hyaluronan: The infamous Cartilage Polyelectrolytes- Then and Now (Anna Plaas, Meghan Moran, John Sandy, Vincent Hascall) -- Chapter 2. Understanding the Influence of Local Physical Stimuli on Chondrocyte Behavior (Byumsu Ki, Lawrence J. Bonassar) -- Chapter 3. Multiscale In Silico Modeling of Cartilage Injuries (Rami K. Korhonen, Atte S.A. Eskelinen, Gustavo A. Orozco, Amir Esrafilian, Cristina Florea, and Petri Tanska) -- Chapter 4. In Vitro Models and Proteomics in Osteoarthritis Research (Martin Rydén, Patrik Önnerfjord) -- Chapter 5. Nanomechanics of Aggrecan: A New Perspective on Cartilage Biomechanics, Disease and Regeneration (Chao Wang, Elizabeth R. Kahle, Lin Han) -- Chapter 6. Computational Modelling for Managing Pathways to Cartilage Failure (Saeed Miramini, David W. Smith, Bruce S. Gardiner, Lihai Zhang) -- Chapter 7. Gene Delivery to Chondrocytes (Christopher V. Nagelli, Christopher H. Evans, Rodolfo E. De la Vega) -- Chapter 8. Mechanical Articular Cartilage Injury Models and Their Relevance in Advancing Therapeutic Strategies (Bodo Kurz, Melanie L Hart, Bernd Rolauffs) -- Chapter 9. Hip Osteoarthritis: Bench to Bedside Perspective (Young-Jo Kim) -- Chapter 10. Harnessing Growth Factor Interactions to Optimize Articular Cartilage Repair (Stephen B. Trippel) -- Personal Tributes -- Index.
506 0 _aOpen Access
520 _aThis is an open access book. In honor of his 75th birthday, we reflect on the impact of the pioneering work of Alan Grodzinsky and his laboratory. This volume includes in-depth discussions of tissue electromechanics, mechanobiology and biomechanics, and matrix biology in addition to the latest advancements in understanding the pathogenesis, progression and treatment of osteoarthritis. Unique to this volume, we overview decades of groundbreaking research that set the stage for the latest efforts in the field, highlighting the legacy of one researcher and their trainees.
650 0 _aMedicine
_xResearch.
650 0 _aBiology
_xResearch.
650 0 _aBiophysics.
650 0 _aBiomechanics.
650 0 _aImmunology.
650 0 _aBones.
650 0 _aBiomedical engineering.
650 1 4 _aBiomedical Research.
650 2 4 _aBiophysics.
650 2 4 _aBiomechanics.
650 2 4 _aOsteoimmunology.
650 2 4 _aBiomedical Engineering and Bioengineering.
700 1 _aConnizzo, Brianne K.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aHan, Lin.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aSah, Robert L.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783031255878
776 0 8 _iPrinted edition:
_z9783031255892
776 0 8 _iPrinted edition:
_z9783031255908
830 0 _aAdvances in Experimental Medicine and Biology,
_x2214-8019 ;
_v1402
856 4 0 _uhttps://doi.org/10.1007/978-3-031-25588-5
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